The SIGMOID project is
intended to produce a database of
cellular signaling pathways and models thereof, to marshall the
major forms of data and knowledge required as input to cellular
modeling software and also to organize the outputs. Such
cellular signaling and regulatory pathways are commonly hand-drawn
in biological literature as an aid to intuitive understanding.
Pathway databases can provide the same assistance in
the context of attempts to achieve a quantitative understanding
of cellular processes by numerical simulation. They can also serve
as an aid to capturing and querying both expert knowledge and
heterogeneous data sets pertaining to pathways. Cell model
databases are a subject of current research. SIGMOID works
at the interface of these two areas.